The Holmes lab is seeking highly motivated individuals who are passionate about uncovering the glial mechanisms driving neurodegeneration. Members of our team have the opportunity to contribute to cutting-edge research, using innovative techniques in proteomics, protein engineering, iPSC biology, and functional genomics. We welcome individuals with diverse backgrounds and expertise to join us in advancing our understanding of neurodegenerative diseases and developing potential therapeutic interventions. Please contact Dr. Brandon Holmes to inquire about possible research projects, open positions, or volunteer opportunites. 

Additionally, we are seeking a candidate to join our quick-paced and multi-talented team to develop therapeutic antibodies to treat autoimmune encephalitis and other inflammatory diseases of the brain. The successful candidate will be responsible for molecular biology, biochemistry, protein and antibody expression and purification, phage display, and protein and antibody validation. The candidate will have opportunities to learn state-of-the-art techniques, including automation systems, and will jointly work within the Neuroscience laboratory led by Dr. Brandon Holmes and the Antibiome Center led by Dr. Kevin Leung. Together, we aim to engineer therapeutic antibodies to target and neutralize pathogenic autoantibodies in neuroinflammatory diseases such as NMDA receptor encephalitis. 

Applications can be submitted at the following portal.